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Products > Diagnostics/Immunoassays > Aquamax-Digoxin Conjugate

Product

Digoxin conjugated to Aquamax-Aequorin

 

 

Application/Background

 

Digoxin is a cardiac glycoside used in the treatment of congestive heart failure and supraventricular arrhythmias. It has a narrow therapeutic window of 0.8- 2.0 ng/mL with a potential fatal toxicity. Therefore, frequent therapeutic drug monitoring is needed. The Aquamax-Digoxin conjugate can be effectively used in the assays requiring real sample analysis, and more importantly, no pretreatment of the samples is required.

Dose-response curve for digoxin in serum

In a solid-phase immunoassay using the Aquamax-Digoxin conjugate a detection limit of 1 x 10-12 with a dynamic range of four orders of magnitude was obtained (1).


For package size, pricing and availability please contact us.  We can customize your order to your requirements.

 

 

REFERENCES:

 

1.    S. Shrestha, I. R. Paeng, S. K. Deo, and S. Daunert. “Cysteine-Free Mutant of Aequorin as a Photolabel in Immunoassay Developement”, Bioconjug. Chem. 13, 269-275, 2002.
   

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Last modified: 06/22/2005